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Site Directed Mutagenesis

Product picture of PCRBIO HiFi Polymerase

Site Directed Mutagensis

Site directed mutagenesis is an in vitro method for introducing specific and intentional mutations into DNA fragments. It is often performed using PCR-based methods due to its speed, simplicity and high efficiency.

Site directed mutagenesis using PCR has become an essential tool for studies of key sequences in regulatory regions and/or the relationship between the structure and function of proteins. PCR Biosystems offers a range of high fidelity DNA polymerases with low error rates that can be used in site directed mutagenesis workflows to ensure accurate amplification.

PCRBIO HS VeriFi™ Polymerase & Mixes

Our most versatile proofreading enzyme now with AptaLock™ hot start technology for maximised specificity in your high fidelity PCR. Ideal for multiplex reactions and room-temperature setup.

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PCRBIO VeriFi™ Polymerase & Mixes

Our highest fidelity enzyme, ideal for cloning, sequencing and site-directed mutagenesis. Get better, more consistent results, even with long and difficult templates.

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PCRBIO HiFi Polymerase

Our original Pfu-derived high fidelity enzyme, PCRBIO HiFi Polymerase brings robust and reliable performance to the world of high fidelity PCR.

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PCRBIO Ultra Polymerase & Mixes

Is your template GC-rich? Or low in abundance? Does your sample contain PCR inhibitors? PCRBIO Ultra Polymerase is engineered to tackle these hard to amplify templates.

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