Introducing IsoFast™ Hot Start Polymerase

Boost sensitivity, specificity and speed in all isothermal amplification workflows

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Power up your 1-step RT-qPCR

Get better results, faster, with Clara™ Probe 1-Step Mix

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We’re the PCR experts – developing high-performance PCR reagents to simplify your research and power your diagnostics

Application Note

Quantifying CpG methylation using MS-HRM qPCR

DNA methylation is an epigenetic process through which nucleobases (mainly cytosines) are modified by the addition of a methyl group.

This mechanism has essential roles in cellular processes including regulation of gene expression, development, and disease. In this application note we describe a workflow for the analysis of DNA methylation in specific loci using methylation-sensitive high-resolution melting (MS-HRM) qPCR.

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Product Launch

VeriFi™ Library Amplification Mix

A specially formulated 2x ready mix designed for NGS library amplification with reduced GC bias.

VeriFi™ Library Amplification Mix combines the powerful proofreading performance of VeriFi Hot Start Polymerase with a greatly reduced GC-dependent bias to push the limits of NGS data quality when sequencing ever longer and more complex targets.   

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